CID-663143
CID-663143 targets microtubule-associated proteins, not tubulin itself, to inhibit the polymerization process within cells. CID-663143 inhibits cancer cell growth (IC50: <100 nM for HT-1080, BJeLR, MCF10A cells).
For research use only. We do not sell to patients.
- CAS No.: 578723-96-3
- Formula: C19H18N4O2S
- Molecular Weight:366.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HT-1080 | EC50 |
<100 nM
Compound: 2, CID 663143
|
Growth inhibition of human HT1080 cells after 24 hrs by alamar blue assay
Growth inhibition of human HT1080 cells after 24 hrs by alamar blue assay
|
[PMID: 22247791] |
| MCF-10A | EC50 |
<100 nM
Compound: 2, CID 663143
|
Growth inhibition of human MCF10A cells after 24 hrs by alamar blue assay
Growth inhibition of human MCF10A cells after 24 hrs by alamar blue assay
|
[PMID: 22247791] |
Chemical Information
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CAS No. 578723-96-3
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Molecular Weight 366.44
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Formula C19H18N4O2S
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SMILES
COC1=C(C=CC=C1)C2=NN=C3SCC(C4=CC=C(OCC)C=C4)=NN23
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)