69563-88-8
69563-88-8
Chemical Structure
GI-530159
- CAS No.: 69563-88-8
- Formula:C27H20F6N2O2
- Molecular Weight:518.45
IUPAC Name: 4,4'-(((perfluoropropane-2,2-diyl)bis(4,1-phenylene))bis(oxy))dianiline
InChIKey: HHLMWQDRYZAENA-UHFFFAOYSA-N
SMILES: FC(C(C1=CC=C(OC2=CC=C(N)C=C2)C=C1)(C3=CC=C(OC4=CC=C(N)C=C4)C=C3)C(F)(F)F)(F)F
Biological Activity: GI-530159 is a selective opener of TREK1 and TREK2 potassium channels. GI-530159 displays selectivity for TREK1/2 over TRAAK, TASK3 and other potassium channels, with an EC50 of 0.76 μM for TREK1. GI-530159 reduces rat dorsal root ganglion neuron excitability and shows potential analgesic effect[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GI-530159 | 99.45% | GI-530159 is a selective opener of TREK1 and TREK2 potassium channels. GI-530159 displays selectivity for TREK1/2 over TRAAK, TASK3 and other potassium channels, with an EC50 of 0.76 μM for TREK1. GI-530159 reduces rat dorsal root ganglion neuron excitability and shows potential analgesic effect. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.69
HY-W0086804,4'-Bis(4-aminophenoxy)biphenyl -
Similarity Score 0.59
HY-W654078Bisphenol AF-13C12 -
Similarity Score 0.55
HY-W0805632,2-Bis(4-carboxyphenyl)hexafluoropropane -
Similarity Score 0.54
HY-W4563604,4'-(1,4-Phenylenebis(oxy))dibenzoic acid -
Similarity Score 0.54
HY-W0753404,4',4''-(Benzene-1,3,5-triyltris(oxy))tribenzoic acid -
Similarity Score 0.54
HY-114641ABIIL-260 hydrochloride -
Similarity Score 0.53
HY-114641BIIL-260 -
Similarity Score 0.53
HY-W0750821,1,2,2-Tetrakis(4-methoxyphenyl)ethene -
Similarity Score 0.52
HY-160793NSC80734 -
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