69563-88-8
69563-88-8
Chemical Structure
GI-530159
- CAS No.: 69563-88-8
- Formula:C27H20F6N2O2
- Molecular Weight:518.45
IUPAC Name: 4,4'-(((perfluoropropane-2,2-diyl)bis(4,1-phenylene))bis(oxy))dianiline
InChIKey: HHLMWQDRYZAENA-UHFFFAOYSA-N
SMILES: FC(C(C1=CC=C(OC2=CC=C(N)C=C2)C=C1)(C3=CC=C(OC4=CC=C(N)C=C4)C=C3)C(F)(F)F)(F)F
Biological Activity: GI-530159 is a selective opener of TREK1 and TREK2 potassium channels. GI-530159 displays selectivity for TREK1/2 over TRAAK, TASK3 and other potassium channels, with an EC50 of 0.76 μM for TREK1. GI-530159 reduces rat dorsal root ganglion neuron excitability and shows potential analgesic effect[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GI-530159 | 99.45% | GI-530159 is a selective opener of TREK1 and TREK2 potassium channels. GI-530159 displays selectivity for TREK1/2 over TRAAK, TASK3 and other potassium channels, with an EC50 of 0.76 μM for TREK1. GI-530159 reduces rat dorsal root ganglion neuron excitability and shows potential analgesic effect. | ||||||||||||||||||||
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