701224-63-7
701224-63-7
Chemical Structure
GLX481304
- CAS No.: 701224-63-7
- Formula:C23H29N7O
- Molecular Weight:419.52
InChIKey: STKSULQULJWEMU-UHFFFAOYSA-N
SMILES: CC1=CC(NC2=NC(N)=NC(CN3CCN(CC3)C4=CC(OC)=CC=C4)=N2)=CC=C1C
Biological Activity: GLX481304 is a specific inhibitor of Nox-2 and -4, with IC50s of 1.25 μM. GLX481304 suppresses ROS production in isolated mouse cardiomyocytes and improves cardiomyocyte contractility. GLX481304 can be used for research of ischemic injury to the heart[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GLX481304 | 98.94% | GLX481304 is a specific inhibitor of Nox-2 and -4, with IC50s of 1.25 μM. GLX481304 suppresses ROS production in isolated mouse cardiomyocytes and improves cardiomyocyte contractility. GLX481304 can be used for research of ischemic injury to the heart. | ||||||||||||||||||||
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Structural Analogs
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Similarity Score 0.83
HY-148936GLX481372 -
Similarity Score 0.70
HY-163279Fluopipamine -
Similarity Score 0.61
HY-124795FPMINT -
Similarity Score 0.60
HY-116785BRD32048 -
Similarity Score 0.56
HY-116941A-381393 -
Similarity Score 0.53
HY-162891EGFR-IN-123 -
Similarity Score 0.52
HY-153592Therapeutic agent-1 -
Similarity Score 0.51
HY-162808GTSE1-IN-1 -
Similarity Score 0.51
HY-144653PDGFR-IN-1 -
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