70563-58-5
Chemical Structure
Herbimycin A
- CAS No.: 70563-58-5
- Formula:C30H42N2O9
- Molecular Weight:574.66
IUPAC Name: (4E,6Z,8S,9S,10E,12S,13R,14S,16S,17R)-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
InChIKey: MCAHMSDENAOJFZ-BVXDHVRPSA-N
SMILES: CO[C@H]([C@H](C[C@@H]([C@@H]([C@H](/C=C([C@@H]1OC(N)=O)\C)C)OC)OC)C)C(C(C(NC(/C(C)=C/C=C\[C@@H]1OC)=O)=C2)=O)=CC2=O
Biological Activity: Herbimycin A, an ansamycin antibiotic, acts as a Src family kinase inhibitor. Herbimycin A binds to the SH domain and inhibits the activity of p60v-src and p210BCR-ABL Herbimycin A inhibits Hsp90 and impairs recovery from heat shock. Herbimycin A exhibits antiangiogenic activity in endothelial cells in vitro.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Herbimycin A | 99% | Herbimycin A, an ansamycin antibiotic, acts as a Src family kinase inhibitor. Herbimycin A binds to the SH domain and inhibits the activity of p60v-src and p210BCR-ABL Herbimycin A inhibits Hsp90 and impairs recovery from heat shock. Herbimycin A exhibits antiangiogenic activity in endothelial cells in vitro. | ||||||||||||||||||||
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Keywords
