71335-86-9
71335-86-9
Chemical Structure
NSC156565
- CAS No.: 71335-86-9
- Formula:C22H17NO4
- Molecular Weight:359.37
InChIKey: HEIUNTCQZMXSDO-UHFFFAOYSA-N
SMILES: OC1=C2C(C3=C(C(C2=C(C=C1)NC4=CC=C(C=C4)CCO)=O)C=CC=C3)=O
Biological Activity: NSC156565 is a Pycsar immune system inhibitor and phage infection potentiator. NSC156565 blocks PycTM cytotoxic effects via prevention of 3′,5′-cCMP-mediated activation or inhibition of activated effector membrane-perturbing activity. NSC156565 enables bacteriophage Bas34 to overcome Pycsar-mediated resistance, facilitating productive phage infection and replication[1].
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NSC156565 | NSC156565 is a Pycsar immune system inhibitor and phage infection potentiator. NSC156565 blocks PycTM cytotoxic effects via prevention of 3′,5′-cCMP-mediated activation or inhibition of activated effector membrane-perturbing activity. NSC156565 enables bacteriophage Bas34 to overcome Pycsar-mediated resistance, facilitating productive phage infection and replication. | |||||||||||||||||||||
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