72786-12-0
72786-12-0
Chemical Structure
Mesulergine hydrochloride
Synonym(s): CU32-085 hydrochloride
- CAS No.: 72786-12-0
- Formula:C18H27ClN4O2S
- Molecular Weight:398.95
InChIKey: HANSYUJEPWNHIM-IVMONYBCSA-N
SMILES: CN1C2=C3C([C@]4([H])[C@@](N(C[C@H](C4)NS(N(C)C)(=O)=O)C)([H])CC3=C1)=CC=C2.Cl
Biological Activity: Mesulergine (CU32-085) hydrochloride is a potent 5-HT2C antagonist and dopamine (DA) agonist. Mesulergine hydrochloride presentes hyperphagia. Mesulergine hydrochloride has the potential for the research of cognitive processes[1][2].
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Mesulergine hydrochloride | Mesulergine (CU32-085) hydrochloride is a potent 5-HT2C antagonist and dopamine (DA) agonist. Mesulergine hydrochloride presentes hyperphagia. Mesulergine hydrochloride has the potential for the research of cognitive processes. | |||||||||||||||||||||
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References
- [1]. Giannakopoulos G, et al. Effects of mesulergine treatment on diet selection, brain serotonin (5-HT) and dopamine (DA) turnover in free feeding rats. Prog Neuropsychopharmacol Biol Psychiatry. 1998 Jul;22(5):803-13. [Content Brief]
- [2]. Khaliq S, et al. Influence of serotonergic 5-HT2C receptor antagonist mesulergine in the reversal of memory deficits induced by mCPP. J Coll Physicians Surg Pak. 2012 Feb;22(2):75-9. [Content Brief]
Keywords
