739301-85-0
739301-85-0
Chemical Structure
NSC45586
- CAS No.: 739301-85-0
- Formula:C20H18N6O3
- Molecular Weight:390.40
IUPAC Name: 5-((E)-(4-((E)-(2,4-diamino-5-methylphenyl)diazenyl)phenyl)diazenyl)-2-hydroxybenzoic acid
InChIKey: LNPJMIMLAFXLSJ-OGGGYYITSA-N
SMILES: O=C(O)C1=CC(/N=N/C2=CC=C(/N=N/C3=CC(C)=C(N)C=C3N)C=C2)=CC=C1O
Biological Activity: NSC45586 is an inhibitor of pleckstrin homology domain and leucine-rich repeat protein phosphatase (PHLPP). NSC45586 targets the PP2C phosphatase domain in PHLPP1 and PHLPP2. NSC45586 can activate AKT in neurons[1].
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NSC45586 | NSC45586 is an inhibitor of pleckstrin homology domain and leucine-rich repeat protein phosphatase (PHLPP). NSC45586 targets the PP2C phosphatase domain in PHLPP1 and PHLPP2. NSC45586 can activate AKT in neurons. | |||||||||||||||||||||
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References
Keywords
