745055-86-1
745055-86-1
Chemical Structure
UBP296
- CAS No.: 745055-86-1
- Formula:C15H15N3O6
- Molecular Weight:333.30
IUPAC Name: 2-((3-(2-amino-2-carboxyethyl)-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl)methyl)benzoic acid
InChIKey: UUIYULWYHDSXHL-UHFFFAOYSA-N
SMILES: O=C(N(C=CC1=O)CC(N)C(O)=O)N1CC2=C(C=CC=C2)C(O)=O
Biological Activity: UBP296 is a potent and selective antagonist of GLUK5-containing kainate receptor in the spinal cord. UBP296 reversibly blocks ATPA-induced depressions of synaptic transmission, and affects AMPA receptor-mediated synaptic transmission directly in rat hippocampal slices[1].
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UBP296 | UBP296 is a potent and selective antagonist of GLUK5-containing kainate receptor in the spinal cord. UBP296 reversibly blocks ATPA-induced depressions of synaptic transmission, and affects AMPA receptor-mediated synaptic transmission directly in rat hippocampal slices. | |||||||||||||||||||||
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References
Keywords
