749269-77-0
749269-77-0
Chemical Structure
CHF5022
- CAS No.: 749269-77-0
- Formula:C17H12F4O2
- Molecular Weight:324.27
IUPAC Name: 1-(2-fluoro-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)cyclopropane-1-carboxylic acid
InChIKey: STSYUQWYKFKDNG-UHFFFAOYSA-N
SMILES: O=C(C1(C2=CC=C(C3=CC=C(C(F)(F)F)C=C3)C(F)=C2)CC1)O
Biological Activity: CHF5022 is an inhibitor of Aβ42 secretion (IC50=92 μM). CHF5022 retains a modest activity on Aβ40 at non-cytotoxic concentrations (−22.2±4.8% at 100 μM)[1].
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CHF5022 | CHF5022 is an inhibitor of Aβ42 secretion (IC50=92 μM). CHF5022 retains a modest activity on Aβ40 at non-cytotoxic concentrations (−22.2±4.8% at 100 μM). | |||||||||||||||||||||
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