7521-41-7
7521-41-7
Chemical Structure
2-Aminonicotinaldehyde
- CAS No.: 7521-41-7
- Formula:C6H6N2O
- Molecular Weight:122.13
IUPAC Name: 2-aminonicotinaldehyde
InChIKey: NXMFJCRMSDRXLD-UHFFFAOYSA-N
SMILES: O=CC1=C(N)N=CC=C1
Biological Activity: 2-Aminonicotinaldehyde is a synthetic intermediate. 2-Aminonicotinaldehyde can be used for the synthesis of 5-HT3 receptor antagonists, AKT inhibitors, and other compounds. 2-Aminonicotinaldehyde is applicable to research on depression and cancers (including hepatocellular carcinoma)[1][2][3].
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2-Aminonicotinaldehyde | 99.98% | 2-Aminonicotinaldehyde is a synthetic intermediate. 2-Aminonicotinaldehyde can be used for the synthesis of 5-HT3 receptor antagonists, AKT inhibitors, and other compounds. 2-Aminonicotinaldehyde is applicable to research on depression and cancers (including hepatocellular carcinoma). | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.85
HY-327912-Chloronicotinaldehyde -
Similarity Score 0.79
HY-328132-Amino-3-iodopyridine -
Similarity Score 0.79
HY-W0077942-Amino-3-hydroxypyridine -
Similarity Score 0.79
HY-W0103092-Chloroisonicotinaldehyde -
Similarity Score 0.77
HY-76735Methyl 2-aminonicotinate -
Similarity Score 0.77
HY-327866-Bromonicotinaldehyde -
Similarity Score 0.77
HY-W008175R2-Amino-5-bromobenzaldehyde (Standard) -
Similarity Score 0.76
HY-W0768364-Aminobenzaldehyde -
Similarity Score 0.75
HY-W0078462-Iodobenzaldehyde -
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References
- [1]. Mahesh R, et al. Design, synthesis and evaluation of antidepressant activity of novel 2-methoxy 1, 8 naphthyridine 3-carboxamides as 5-HT3 receptor antagonists. Chem Biol Drug Des. 2014;83(5):583-591. [Content Brief]
- [2]. Zhang Z, et al. Design, Synthesis, and Biological Evaluation of 2-Formyl Tetrahydronaphthyridine Urea Derivatives as New Selective Covalently Reversible FGFR4 Inhibitors. J Med Chem. 2022;65(4):3249-3265. [Content Brief]
- [3]. Jean-Marc Lapierre, et al. Discovery of 3-(3-(4-(1-Aminocyclobutyl)phenyl)-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine (ARQ 092): An Orally Bioavailable, Selective, and Potent Allosteric AKT Inhibitor. Journal of Medicinal Chemistry 2016 59 (13), 6455-6469
