75444-65-4
75444-65-4
Chemical Structure
Pirenperone
Synonym(s): R 47465
- CAS No.: 75444-65-4
- Formula:C23H24FN3O2
- Molecular Weight:393.45
IUPAC Name: 3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
InChIKey: HXCNRYXBZNHDNE-UHFFFAOYSA-N
SMILES: O=C1C(CCN2CCC(C(C3=CC=C(F)C=C3)=O)CC2)=C(C)N=C4N1C=CC=C4
Biological Activity: Pirenperone (R 47465) is a 5-HT2 serotonin receptor antagonist. Pirenperone exhibits modest anxiolytic activity[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pirenperone | 98.97% | Pirenperone (R 47465) is a 5-HT2 serotonin receptor antagonist. Pirenperone exhibits modest anxiolytic activity. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.86
HY-121311Metrenperone -
Similarity Score 0.68
HY-169127Seganserin -
Similarity Score 0.65
HY-119800Setoperone -
Similarity Score 0.62
HY-10562Ketanserin -
Similarity Score 0.61
HY-119156RAltanserin (Standard) -
Similarity Score 0.61
HY-103139Altanserin hydrochloride -
Similarity Score 0.59
HY-105798Butanserin -
Similarity Score 0.58
HY-107613RR 59-022 (Standard) -
Similarity Score 0.58
HY-121898Milenperone -
Explore the MedChemAI to find more analogs
References
- [1]. Krstić MK, et, al. Divergent effects of pirenperone, a 5-HT2 antagonist, on the pressor and tachycardic responses to 5-HT in guinea-pigs. Arch Int Physiol Biochim. 1983 Nov;91(4):345-9. [Content Brief]
- [2]. Ansseau M, et, al. Pilot study of a specific serotonergic antagonist, pirenperone, in the treatment of anxiety disorders. Acta Psychiatr Belg. Sep-Oct 1983;83(5):517-24. [Content Brief]
