76656-80-9
Chemical Structure
3′,6-Disinapoylsucrose
- CAS No.: 76656-80-9
- Formula:C34H42O19
- Molecular Weight:754.69
IUPAC Name: (2S,3S,4R,5R)-4-hydroxy-2,5-bis(hydroxymethyl)-2-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((E)-3-(4-hydroxy-3,5-dimethoxyphenyl)acryloyl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydrofuran-3-yl (E)-3-(4-hydroxy-3,5-dimethoxyphenyl)acrylate
InChIKey: FHIJMQWMMZEFBL-OPSYHMPNSA-N
SMILES: OC[C@@]1([C@H]([C@@H]([C@H](O1)CO)O)OC(/C=C/C2=CC(OC)=C(C(OC)=C2)O)=O)O[C@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)COC(/C=C/C4=CC(OC)=C(C(OC)=C4)O)=O
Biological Activity: 3′,6-Disinapoylsucrose is a type of oligosaccharide that's effective when taken orally, and it has antidepressant, anti-anxiety, and antioxidant properties. 3′,6-Disinapoylsucrose inhibits neuronal apoptosis by lowering the ratio of Bax to Bcl-2 in hippocampal neurons, and it enhances cognitive function in APP/PS1 transgenic mice by activating the CREB/BDNF signaling pathway[1][2].
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3′,6-Disinapoylsucrose | 98.88% | 3′,6-Disinapoylsucrose is a type of oligosaccharide that's effective when taken orally, and it has antidepressant, anti-anxiety, and antioxidant properties. 3′,6-Disinapoylsucrose inhibits neuronal apoptosis by lowering the ratio of Bax to Bcl-2 in hippocampal neurons, and it enhances cognitive function in APP/PS1 transgenic mice by activating the CREB/BDNF signaling pathway. | ||||||||||||||||||||
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References
- [1]. Jiaqi Yuan, et al. 3,6'-Disinapoyl sucrose alleviates cognitive deficits in APP/PS1 transgenic mice. J Neurophysiol. 2023 Nov 1;130(5):1174-1182. [Content Brief]
- [2]. Jie Zhang, et al. Anxiolytic effects, metabolism and plasma pharmacokinetics of 3, 6' -disinapoylsucrose. Biomed Pharmacother. 2022 May:149:112913. [Content Brief]
