78080-27-0
78080-27-0
Chemical Structure
PET-cGMP
- CAS No.: 78080-27-0
- Formula:C18H16N5O7P
- Molecular Weight:445.32
IUPAC Name: 3-((4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl)-6-phenyl-3,4-dihydro-9H-imidazo[1,2-a]purin-9-one
InChIKey: TVSIKYJKUPRIDV-LSCFUAHRSA-N
SMILES: O=C1C2=C(NC3=NC(C4=CC=CC=C4)=CN13)N([C@]5([H])O[C@@](CO[P]6(O)=O)([H])[C@](O6)([H])[C@H]5O)C=N2
Biological Activity: PET-cGMP is a cyclic guanosine monophosphate analog and an effective selective agonist of PKG I, the EC50 of PET-cGMP for PKG Iβ is 3.8 nM, while for PKG II, it's 193 nM[1].
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PET-cGMP | PET-cGMP is a cyclic guanosine monophosphate analog and an effective selective agonist of PKG I, the EC50 of PET-cGMP for PKG Iβ is 3.8 nM, while for PKG II, it's 193 nM. | |||||||||||||||||||||
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References
Keywords
