78950-78-4
78950-78-4
Chemical Structure
8-OH-DPAT
Synonym(s): 8-Hydroxy-DPAT
- CAS No.: 78950-78-4
- Formula:C16H25NO
- Molecular Weight:247.38
IUPAC Name: 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol
InChIKey: ASXGJMSKWNBENU-UHFFFAOYSA-N
SMILES: OC1=C2CC(N(CCC)CCC)CCC2=CC=C1
Biological Activity: 8-OH-DPAT is a potent, brain-penetrant and selective 5-HT agonist, with a pIC50 of 8.19 for 5-HT1A and a Ki of 466 nM for 5-HT7; 8-OH-DPAT weakly binds to 5-HT1B (pIC50, 5.42), 5-HT (pIC50 <5).
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8-OH-DPAT | 99.87% | 8-OH-DPAT is a potent, brain-penetrant and selective 5-HT agonist, with a pIC50 of 8.19 for 5-HT1A and a Ki of 466 nM for 5-HT7; 8-OH-DPAT weakly binds to 5-HT1B (pIC50, 5.42), 5-HT (pIC50 <5). | ||||||||||||||||||||
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8-OH-DPAT (Standard) | ≥98% | 8-OH-DPAT (Standard) is the analytical standard of 8-OH-DPAT. This product is intended for research and analytical applications. 8-OH-DPAT is a potent and selective 5-HT agonist, with a pIC50 of 8.19 for 5-HT1A and a Ki of 466 nM for 5-HT7; 8-OH-DPAT weakly binds to 5-HT1B (pIC50, 5.42), 5-HT (pIC50 <5). | ||||||||||||||||||||
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