796885-38-6
Chemical Structure
MK-4541
- CAS No.: 796885-38-6
- Formula:C22H31F3N2O3
- Molecular Weight:428.49
IUPAC Name: 2,2,2-trifluoroethyl ((4aR,4bS,6aS,7S,9aS,9bS,11aR)-1,4a,6a-trimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinolin-7-yl)carbamate
InChIKey: OGBFNZPDLOPGEO-OCWMMRLVSA-N
SMILES: C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])N(C(C=C2)=O)C)([H])[C@@]4([H])[C@@](C)([C@@H](NC(OCC(F)(F)F)=O)CC4)CC3
Biological Activity: MK-4541 is an orally active and selective androgen receptor (AR) modulator. MK-4541 acts as an antagonist to inhibit 5α-reductase. MK-4541 inhibits proliferation and induces apoptosis in AR positive prostate cancer cells. MK-4541 significantly inhibited the growth of R3327-G prostate tumors in xenograft mouse model[1].
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MK-4541 | MK-4541 is an orally active and selective androgen receptor (AR) modulator. MK-4541 acts as an antagonist to inhibit 5α-reductase. MK-4541 inhibits proliferation and induces apoptosis in AR positive prostate cancer cells. MK-4541 significantly inhibited the growth of R3327-G prostate tumors in xenograft mouse model. | |||||||||||||||||||||
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Keywords
