849479-60-3
Chemical Structure
Glycyl-Exatecan
Synonym(s): Glycyl-DX-8951; Exatecan analog 2
- CAS No.: 849479-60-3
- Formula:C26H25FN4O5
- Molecular Weight:492.50
IUPAC Name: 2-amino-N-((1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl)acetamide
InChIKey: ZDCWCSNUHWGLRH-QLXKLKPCSA-N
SMILES: NCC(N[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(F)=C(C)C(CC1)=C62)=O
Biological Activity: Glycyl-Exatecan (Glycyl-DX-8951) is an active metabolite released from DE-310 by enzymatic cleavage of the spacer. Glycyl-Exatecan exerts anti-tumor activity in vivo. Glycyl-Exatecan can be used for solid tumor research[1].
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Glycyl-Exatecan | Glycyl-Exatecan (Glycyl-DX-8951) is an active metabolite released from DE-310 by enzymatic cleavage of the spacer. Glycyl-Exatecan exerts anti-tumor activity in vivo. Glycyl-Exatecan can be used for solid tumor research. | |||||||||||||||||||||
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Keywords
