851627-80-0
Chemical Structure
PR-104 sodium
- CAS No.: 851627-80-0
- Formula:C14H19BrN4NaO12PS
- Molecular Weight:601.25
IUPAC Name: sodium 2-(2-((2-bromoethyl)(2-((methylsulfonyl)oxy)ethyl)amino)-3,5-dinitrobenzamido)ethyl hydrogen phosphate
InChIKey: ZHZRUSZTONWGGW-UHFFFAOYSA-M
SMILES: O=C(NCCOP(O)(O[Na])=O)C1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1N(CCBr)CCOS(=O)(C)=O
Biological Activity: PR-104 (sodium) is a selective hypoxia-activated DNA cross-linking agent and can be used for the research of multiple tumor xenograft models. PR-104 (sodium), as a nitrogen mustard pre-proagent, is converted efficiently to the more lipophilic dinitrobenzamide mustards alcohol PR-104A[1].
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PR-104 sodium | PR-104 (sodium) is a selective hypoxia-activated DNA cross-linking agent and can be used for the research of multiple tumor xenograft models. PR-104 (sodium), as a nitrogen mustard pre-proagent, is converted efficiently to the more lipophilic dinitrobenzamide mustards alcohol PR-104A. | |||||||||||||||||||||
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Keywords