86303-26-6
Chemical Structure
Biotin-16-dUTP
Synonym(s): Biotin-16-deoxyuridine-5'-triphosphate
- CAS No.: 86303-26-6
- Formula:C32H52N7O18P3S
- Molecular Weight:947.78
IUPAC Name: ((2R,3S,5R)-5-(2,4-dioxo-5-((E)-3-(6-(4-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)butanamido)hexanamido)prop-1-en-1-yl)-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
InChIKey: APUCJHHBLIXMRI-YGXOHKNQSA-N
SMILES: O[C@H]1C[C@H](N(C=C2/C=C/CNC(CCCCCNC(CCCNC(CCCC[C@@H]3SC[C@@]4(NC(N[C@@]43[H])=O)[H])=O)=O)=O)C(NC2=O)=O)O[C@@H]1COP(O)(OP(O)(OP(O)(O)=O)=O)=O
Biological Activity: Biotin-16-dUTP (Biotin-16-deoxyuridine-5'-triphosphate) can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP can be used to produce biotinylated DNA probes in a variety of assay applications[1][2].
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Biotin-16-dUTP | Biotin-16-dUTP (Biotin-16-deoxyuridine-5'-triphosphate) can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP can be used to produce biotinylated DNA probes in a variety of assay applications. | |||||||||||||||||||||
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References
- [1]. C Charriaut-Marlangue, et al. A cautionary note on the use of the TUNEL stain to determine apoptosis. Neuroreport. 1995 Dec 29;7(1):61-4. [Content Brief]
- [2]. T Krude, et al. Chromatin assembly factor 1 (CAF-1) colocalizes with replication foci in HeLa cell nuclei. Exp Cell Res. 1995 Oct;220(2):304-11. [Content Brief]
