866541-93-7
866541-93-7
Chemical Structure
(R)-(-)-Gossypol acetic acid
Synonym(s): AT-101 (acetic acid); (-)-Gossypol acetic acid; (R)-Gossypol acetic acid
- CAS No.: 866541-93-7
- Formula:C32H34O10
- Molecular Weight:578.61
SMILES: OC1=C2C(C=O)=C(O)C(O)=C(C(C)C)C2=CC(C)=[C@]1[C@]3=C(C)C=C4C(C(C)C)=C(O)C(O)=C(C=O)C4=C3O.CC(O)=O
Biological Activity: (R)-(-)-Gossypol acetic acid (AT-101 (acetic acid)) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to Bcl-2, Mcl-1 and Bcl-xL proteins with Kis of 260±30 nM, 170±10 nM, and 480±40 nM, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(R)-(-)-Gossypol acetic acid | 98.93% | (R)-(-)-Gossypol acetic acid (AT-101 (acetic acid)) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to Bcl-2, Mcl-1 and Bcl-xL proteins with Kis of 260±30 nM, 170±10 nM, and 480±40 nM, respectively. | ||||||||||||||||||||
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Keywords
