86770-68-5
Chemical Structure
Azido-PEG5-alcohol
- CAS No.: 86770-68-5
- Formula:C10H21N3O5
- Molecular Weight:263.29
IUPAC Name: 14-azido-3,6,9,12-tetraoxatetradecan-1-ol
InChIKey: JTGGTGKXQQGEHB-UHFFFAOYSA-N
SMILES: OCCOCCOCCOCCOCCN=[N+]=[N-]
Biological Activity: Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG5-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Azido-PEG5-alcohol | 97.0% | Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG5-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | ||||||||||||||||||||
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Similarity Score 0.93
HY-140809Azido-PEG4-(CH2)3OH -
Similarity Score 0.92
HY-130537Azido-PEG6-alcohol -
Similarity Score 0.92
HY-128834N3-PEG4-C2-NH2 -
Similarity Score 0.92
HY-140821Bromo-PEG4-azide -
Similarity Score 0.91
HY-138525Azido-PEG4-Thiol -
Similarity Score 0.90
HY-130168m-PEG5-azide -
Similarity Score 0.89
HY-140842Azido-PEG4-nitrile -
Similarity Score 0.89
HY-126950Aminooxy-PEG4-azide -
Similarity Score 0.88
HY-130653Azido-PEG4-C2-acid -
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