870640-64-5
870640-64-5
Chemical Structure
Monomethyl auristatin E intermediate-13
- CAS No.: 870640-64-5
- Formula:C21H35NO3
- Molecular Weight:349.51
IUPAC Name: (3R,4S,5S)-tert-butyl 4-(benzyl(methyl)amino)-3-methoxy-5-methylheptanoate
InChIKey: FJVJLCHQFIDUCO-HQRMLTQVSA-N
SMILES: CC[C@H](C)[C@H](N(CC1=CC=CC=C1)C)[C@H](OC)CC(OC(C)(C)C)=O
Biological Activity: Monomethyl auristatin E intermediate-13 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
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Monomethyl auristatin E intermediate-13 | Monomethyl auristatin E intermediate-13 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs). | |||||||||||||||||||||
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