871015-11-1
Chemical Structure
4SC-207
- CAS No.: 871015-11-1
- Formula:C19H18N4O3S
- Molecular Weight:382.44
IUPAC Name: ethyl (E)-3-cyano-2-(3-(pyridin-3-yl)acrylamido)-4,7-dihydrothieno[2,3-c]pyridine-6(5H)-carboxylate
InChIKey: KNQCFGQPDILWLT-AATRIKPKSA-N
SMILES: O=C(N1CCC(C(C#N)=C(NC(/C=C/C2=CC=CN=C2)=O)S3)=C3C1)OCC
Biological Activity: 4SC-207 is a potent, orally active microtubule inhibitor. 4SC-207 inhibits microtubule growth to inhibit tumor cell proliferation in vitro and in vivo, and promotes a mitotic delay/arrest, followed by apoptosis or aberrant divisions. 4SC-207 inhibits tumor growth in taxane resistant xenograft mouse models. 4SC-207 can be used for cancer research, such as colon adenocarcinoma and other malignancies[1].
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4SC-207 | 4SC-207 is a potent, orally active microtubule inhibitor. 4SC-207 inhibits microtubule growth to inhibit tumor cell proliferation in vitro and in vivo, and promotes a mitotic delay/arrest, followed by apoptosis or aberrant divisions. 4SC-207 inhibits tumor growth in taxane resistant xenograft mouse models. 4SC-207 can be used for cancer research, such as colon adenocarcinoma and other malignancies. | |||||||||||||||||||||
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Keywords
