871037-95-5
Chemical Structure
TTT 3002
- CAS No.: 871037-95-5
- Formula:C27H23N5O3
- Molecular Weight:465.50
IUPAC Name: (5S,6R,8R)-6-amino-N,5-dimethyl-13-oxo-5,6,7,8,14,15-hexahydro-13H-16-oxa-4b,8a,14-triaza-5,8-methanodibenzo[b,h]cycloocta[jkl]cyclopenta[e]-as-indacene-6-carboxamide
InChIKey: DCAYZGCTSXLIHO-SOLYNIJKSA-N
SMILES: C[C@]12N3C4=C(C5=CC=CC=C53)C(CNC6=O)=C6C7=C4N([C@](C[C@]2(N)C(NC)=O)([H])O1)C8=CC=CC=C78
Biological Activity: TTT 3002 is a potent and orally active FLT3 inhibitor. TTT 3002 potently inhibits FLT3 phosphorylation by activating mutations at residue D835, with an IC50 of 0.2 nM. TTT 3002 can be used for AML (acute myeloid leukemia) research[1].
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TTT 3002 | TTT 3002 is a potent and orally active FLT3 inhibitor. TTT 3002 potently inhibits FLT3 phosphorylation by activating mutations at residue D835, with an IC50 of 0.2 nM. TTT 3002 can be used for AML (acute myeloid leukemia) research. | |||||||||||||||||||||
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Keywords
