87156-01-2
87156-01-2
Chemical Structure
EDA-DA TFA
- CAS No.: 87156-01-2
- Formula:C10H13F3N2O5
- Molecular Weight:298.22
InChIKey: BRIXKPONTJDKNO-KGZKBUQUSA-N
SMILES: OC(C(F)(F)F)=O.OC([C@@H](C)NC([C@H](N)CC#C)=O)=O
Biological Activity: EDA-DA is a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. EDA-DA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
EDA-DA TFA | 95.0% | EDA-DA is a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. EDA-DA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Cysteinylglycine TFA | 99.76% | Cysteinylglycine (L-Cysteinylglycine; Cys-Gly) TFA is a dipeptide formed by the peptide bond connection of cysteine and glycine. Cysteinylglycine TFA is an important metabolic intermediate in the human body, mainly derived from the degradation of glutathione (GSH). Cysteinylglycine TFA can reduce trivalent iron to divalent iron, driving the redox cycle of iron, generating reactive oxygen species (ROS), stimulating oxidative reactions, inducing lipid peroxidation in human plasma LDL lipoproteins, and causing oxidative damage to DNA base. Cysteinylglycine TFA can be used as a biomarker to assess ischemic heart disease and breast cancer, etc. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Gamma-glutamylcysteine TFA (Standard) | 95.17% | Gamma-glutamylcysteine (TFA) (Standard) is the analytical standard of Gamma-glutamylcysteine (TFA). This product is intended for research and analytical applications. Gamma-glutamylcysteine TFA (γ-Glu-Cys TFA) is an orally active, blood-brain barrier permeable dipeptide. Gamma-glutamylcysteine TFA activates AMPK, SIRT1, IL-4/STAT6, AC/cAMP/PI3K, IGF-1R/IRS1/PI3K, and Nrf2 signaling pathways; it inhibits NF-κB, JAK1/STAT1/3, MAPKs, cadmium-induced p38 MAPK, JNK, and PI3K/Akt signaling pathways. Gamma-glutamylcysteine TFA regulates macrophage polarization, modulates the trafficking of CD36 and GLUT4, induces glutathione synthesis, improves metabolic dysfunction, reduces lipid deposition, ameliorates glucose homeostasis, inhibits apoptosis (Apoptosis), stabilizes mitochondria, suppresses lipid peroxidation, iron accumulation and ferroptosis (Ferroptosis), reduces ds-HMGB1 levels, reverses mechanical hyperalgesia, and alleviates hepatic lipid droplet formation. Gamma-glutamylcysteine TFA is applicable to research related to inflammatory bowel disease, type 2 diabetes, cadmium-induced neurotoxicity, Alzheimer's disease, cerebral ischemia/reperfusion injury, neuropathy, and alcoholic liver disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
gamma-DGG TFA | 99.95% | gamma-DGG TFA is the antagonist for excitatory amino acid, that blocks NMDA-(HY-17551), Kainate-(HY-N2309) and Quisqualate-(HY-12597) induced depolarization, and antagonises the excitatory postsynaptic potential (e.p.s.p.) in rat hippocampal slices. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
N-(2,6-Diamino-6-hydroxymethylpimelyl)-L-alanine | N-(2,6-Diamino-6-hydroxymethylpimelyl)-L-alanine shows anti-Escherichia coli activity, and is combined with several cell wall synthesis inhibitors such as Fosfomycin, Cycloserine, Penicillin, and Cephalosporin, the combination of sporozoin has obvious synergistic antibacterial effect. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
NH2-KAA-COOH | NH2-KAA-COOH is a oligopeptide compoused of Lys-Ala-Ala. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Asp-Val | 98.0% | Asp-Val is a dipeptide formed from L-alpha-aspartyl and L-valine residues. Asp-Val has a role as a metabolite. Asp-Val can be isolated from an enzymatic hydrolysate of food proteins. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
D-{Ala-Ala-Ala} | D-{Ala-Ala-Ala} is a tripeptide. D-{Ala-Ala-Ala} binds to ristocetin to detect bacteria at low concentrations. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Valylleucine TFA | 99.25% | Valylleucine (Val-Leu; H-Val-Leu-OH) TFA is a branched-chain dipeptide that can enter cells independently via bacterial dipeptide transport systems, and is hydrolyzed by dipeptidases to release Val and Leu. Valylleucine TFA, as a model peptide, has its α-amino pK determined to be 7.90 by combining FDNB reaction kinetics with potentiometric titration. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Ala-Ala-Ala | Ala-Ala-Ala is an alanine derivative. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
D-Ala-D-Ala TFA | D-Ala-D-Ala TFA is a bacterial endogenous metabolite. D-Ala-D-Ala TFA constitutes the terminus of the peptide part of the peptidoglycan monomer unit and is involved in the transpeptidation reaction as the substrate. D-Ala-D-Ala TFA is catalyzed by D-Alanine-D-Alanine ligase. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
