873077-70-4
873077-70-4
Chemical Structure
AMPK-IN-4
- CAS No.: 873077-70-4
- Formula:C18H19FN4O2
- Molecular Weight:342.37
InChIKey: MUXSMSOGTBJZDC-JYRVWZFOSA-N
SMILES: O=C(/C(C1=C2)=C\C3=C(C(C(NCCN)=O)=C(N3)C)C)NC1=CC=C2F
Biological Activity: AMPK-IN-4 (compound 19) is a potent inhibitor of (AMPK(α1) and AMPK(α2) with IC50s of 393 nM and 141 nM, respectively. AMPK-IN-4 plays an important role in cancer research[1].
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AMPK-IN-4 | 97.16% | AMPK-IN-4 (compound 19) is a potent inhibitor of (AMPK(α1) and AMPK(α2) with IC50s of 393 nM and 141 nM, respectively. AMPK-IN-4 plays an important role in cancer research. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.89
HY-138032SU11657 -
Similarity Score 0.88
HY-10873N-Desethyl Sunitinib -
Similarity Score 0.87
HY-138813A(E/Z)-N-Desethylsunitinib hydrochloride -
Similarity Score 0.85
HY-10255ASunitinib -
Similarity Score 0.83
HY-10330Toceranib -
Similarity Score 0.82
HY-44856RSunitinib impurity 28 (Standard) -
Similarity Score 0.81
HY-10873SN-Desethyl Sunitinib-d5 -
Similarity Score 0.80
HY-10873S2N-Desethyl Sunitinib-d5 hydrochloride -
Similarity Score 0.77
HY-10330ARToceranib phosphate (Standard) -
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