873318-96-8
Chemical Structure
NGD-4715
- CAS No.: 873318-96-8
- Formula:C25H30F3N3O3
- Molecular Weight:477.52
InChIKey: LLXOFZRGQVSNAP-PZJWPPBQSA-N
SMILES: CC1=C(C=CC(OCCO)=C1C)[C@@H]2N3[C@](CCC2)([H])CN(CC3)C(C4=CN=C(C(F)(F)F)C=C4)=O
Biological Activity: NGD-4715 is an orally effective melanin-concentrating hormone receptor 1 (MCHR1) antagonist with IC50 and Ki values of 10.6 nM and 5.9 nM, respectively. NGD-4715 acts as an inhibitor of food intake, a body weight regulator and a metabolic regulator, and reduces food intake, body weight gain and blood glucose levels in diet-induced obese rats. NGD-4715 is applicable to obesity-related research[1].
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NGD-4715 | NGD-4715 is an orally effective melanin-concentrating hormone receptor 1 (MCHR1) antagonist with IC50 and Ki values of 10.6 nM and 5.9 nM, respectively. NGD-4715 acts as an inhibitor of food intake, a body weight regulator and a metabolic regulator, and reduces food intake, body weight gain and blood glucose levels in diet-induced obese rats. NGD-4715 is applicable to obesity-related research. | |||||||||||||||||||||
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Keywords
