875055-92-8
875055-92-8
Chemical Structure
CH4933468
- CAS No.: 875055-92-8
- Formula:C15H17ClN4O3S2
- Molecular Weight:400.90
IUPAC Name: 3-(3-(3-chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)propane-1-sulfonamide
InChIKey: DSIHXMZSDDJEHM-UHFFFAOYSA-N
SMILES: O=S(CCCN(C(N1C2=CC=C(C#N)C(Cl)=C2)=S)C(C)(C)C1=O)(N)=O
Biological Activity: CH4933468 is a thiohydantoin derivative, shows androgen receptor (AR) pure antagonist activity in vitro. CH4933468 inhibits AR-mediated transactivation and proliferation of LNCaP and LNCaP-BC2 cells. CH4933468 can be used for castration-resistant prostate cancer (CRPC) research[1].
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CH4933468 | CH4933468 is a thiohydantoin derivative, shows androgen receptor (AR) pure antagonist activity in vitro. CH4933468 inhibits AR-mediated transactivation and proliferation of LNCaP and LNCaP-BC2 cells. CH4933468 can be used for castration-resistant prostate cancer (CRPC) research. | |||||||||||||||||||||
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References
Keywords
