875787-07-8
875787-07-8
Chemical Structure
LXR-623
Synonym(s): WAY 252623
- CAS No.: 875787-07-8
- Formula:C21H12ClF5N2
- Molecular Weight:422.78
IUPAC Name: 2-(2-chloro-4-fluorobenzyl)-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole
InChIKey: KYWWJENKIMRJBI-UHFFFAOYSA-N
SMILES: ClC1=C(CN2N=C(C(C(F)(F)F)=CC=C3)C3=C2C4=CC=C(F)C=C4)C=CC(F)=C1
Biological Activity: LXR-623 is a brain-penetrant partial LXRα and full LXRβ agonist, with IC50s of 24 nM and 179 nM, respectively.
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LXR-623 | 99.95% | LXR-623 is a brain-penetrant partial LXRα and full LXRβ agonist, with IC50s of 24 nM and 179 nM, respectively. | ||||||||||||||||||||
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LXR-623 (Standard) | ≥98% | LXR-623 (Standard) is the analytical standard of LXR-623. This product is intended for research and analytical applications. LXR-623 is a brain-penetrant partial LXRα and full LXRβ agonist, with IC50s of 24 nM and 179 nM, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.55
HY-157250BHD -
Similarity Score 0.55
HY-119464MRL-871 -
Similarity Score 0.53
HY-116730CHS-111 -
Similarity Score 0.51
HY-163124HBV-IN-43 -
Similarity Score 0.50
HY-117726WAY-169916 -
Similarity Score 0.49
HY-121721Inz-5 -
Similarity Score 0.49
HY-175035HK-2-IN-1 -
Similarity Score 0.48
HY-183673COX-1/2-IN-12 -
Similarity Score 0.48
HY-123035Gamendazole -
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