875927-64-3
Chemical Structure
UoS12258
- CAS No.: 875927-64-3
- Formula:C17H19FN2O2S
- Molecular Weight:334.41
IUPAC Name: (S)-N-(5-(6-fluoropyridin-3-yl)-2,3-dihydro-1H-inden-2-yl)propane-2-sulfonamide
InChIKey: QXQSUBKWSHMXDP-INIZCTEOSA-N
SMILES: CC(S(=O)(N[C@H]1CC2=C(C=C(C3=CC=C(F)N=C3)C=C2)C1)=O)C
Biological Activity: UoS12258 is a selective positive allosteric modulator of AMPA receptor. UoS12258 enhances AMPA receptor‐mediated synaptic transmission. UoS12258 improves performance in cognition rat models, including Scopolamine (HY-N0296)‐impaired rats and water maze learning and retention in aged rats[1].
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UoS12258 | 99.86% | UoS12258 is a selective positive allosteric modulator of AMPA receptor. UoS12258 enhances AMPA receptor‐mediated synaptic transmission. UoS12258 improves performance in cognition rat models, including Scopolamine (HY-N0296)‐impaired rats and water maze learning and retention in aged rats. | ||||||||||||||||||||
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Keywords