88280-21-1
88280-21-1
Chemical Structure
LPLRF-NH2
- CAS No.: 88280-21-1
- Formula:C32H53N9O5
- Molecular Weight:643.82
InChIKey: NIIZKQVUHKYFML-LROMGURASA-N
SMILES: O=C(N1[C@@H](CCC1)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC2=CC=CC=C2)C(N)=O)=O)=O)=O)[C@H](CC(C)C)N
Biological Activity: LPLRF-NH2 is a member of RFamide peptide with anorexigenic effect. LPLRF-NH2 increases arterial blood pressure and modulates the electrical activity of brainstem neurons[1][2][3].
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LPLRF-NH2 | LPLRF-NH2 is a member of RFamide peptide with anorexigenic effect. LPLRF-NH2 increases arterial blood pressure and modulates the electrical activity of brainstem neurons. | |||||||||||||||||||||
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References
- [1]. Scheel A, et al. LPLRFamide exerts short-term anorexigenic effects that coincide with magnocellular division of the hypothalamic paraventricular nucleus activation. Gen Comp Endocrinol. 2017 May 15;246:116-119. [Content Brief]
- [2]. Barnard CS, et al. Increases in arterial blood pressure in the rat in response to a new vertebrate neuropeptide, LPLRFamide, and a related molluscan peptide, FMRFamide. Regul Pept. 1984 Apr;8(3):209-15. [Content Brief]
- [3]. Chartrel N, et al. Structure and functions of the novel hypothalamic RFamide neuropeptides R-RFa and 26RFa in vertebrates. Peptides. 2006 May;27(5):1110-20. [Content Brief]
