1. Peptides
  2. LPLRF-NH2

LPLRF-NH2 is a member of RFamide peptide with anorexigenic effect. LPLRF-NH2 increases arterial blood pressure and modulates the electrical activity of brainstem neurons.

For research use only. We do not sell to patients.

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LPLRF-NH2 Chemical Structure

LPLRF-NH2 Chemical Structure

CAS No. : 88280-21-1

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Description

LPLRF-NH2 is a member of RFamide peptide with anorexigenic effect. LPLRF-NH2 increases arterial blood pressure and modulates the electrical activity of brainstem neurons[1][2][3].

In Vitro

YMRF-NH2 (0.1 nM-1 μM) inhibits Forskolin-induced production of cAMP in CHO cells[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

LPLRF-NH2 (3-15 nmol, ICV) shows anorexigenic effect in chicks[1].
LPLRF-NH2 (25-50 nM/kg, 150 μL, i.v.) increases arterial blood pressure in rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Chicks[1]
Dosage: 3.0, 7.0 or 15 nmol
Administration: Intracerebroventrical injection (ICV) injection
Result: Decreased food intake.
Increased number of c-Fos reactive cells in the paraventricular nucleus.
Molecular Weight

643.82

Formula

C32H53N9O5

CAS No.
Sequence Shortening

LPLRF-NH2

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
LPLRF-NH2
Cat. No.:
HY-P3593
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