897776-15-7
897776-15-7
Chemical Structure
Inz-1
- CAS No.: 897776-15-7
- Formula:C16H14N2O2
- Molecular Weight:266.29
IUPAC Name: methyl 2-(3-phenyl-1H-indazol-1-yl)acetate
InChIKey: RBYOCUDWQCQSAM-UHFFFAOYSA-N
SMILES: O=C(OC)CN1N=C(C2=CC=CC=C2)C3=C1C=CC=C3
Biological Activity: Inz-1 is a potent and selective mitochondrial cytochrome bc1 inhibitor for yeast (IC50=8.092 μM) over humans (IC50=45.320 μM). Inz-1 reverses Fluconazole (HY-B0101) or other triazole antifungals’ resistance in the pathogenic fungus Candida albicans[1].
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Inz-1 | Inz-1 is a potent and selective mitochondrial cytochrome bc1 inhibitor for yeast (IC50=8.092 μM) over humans (IC50=45.320 μM). Inz-1 reverses Fluconazole (HY-B0101) or other triazole antifungals’ resistance in the pathogenic fungus Candida albicans. | |||||||||||||||||||||
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References
Keywords
