898280-07-4
898280-07-4
Chemical Structure
XL228
- CAS No.: 898280-07-4
- Formula:C22H31N9O
- Molecular Weight:437.54
IUPAC Name: N4-(5-cyclopropyl-1H-pyrazol-3-yl)-N2-((3-isopropylisoxazol-5-yl)methyl)-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine
InChIKey: ALKJNCZNEOTEMP-UHFFFAOYSA-N
SMILES: CN1CCN(C2=CC(NC3=NNC(C4CC4)=C3)=NC(NCC5=CC(C(C)C)=NO5)=N2)CC1
Biological Activity: XL228 is a multi-targeted tyrosine kinase inhibitor with IC50s of 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src and Lyn, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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XL228 | 99.64% | XL228 is a multi-targeted tyrosine kinase inhibitor with IC50s of 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src and Lyn, respectively. | ||||||||||||||||||||
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Keywords
