899548-78-8
Chemical Structure
JMJD6-IN-1
- CAS No.: 899548-78-8
- Formula:C16H11N3O2
- Molecular Weight:277.28
IUPAC Name: 3-(3H-imidazo[4,5-c]pyridin-2-yl)-6-methyl-2H-chromen-2-one
InChIKey: AFTXOIIKGOXDOT-UHFFFAOYSA-N
SMILES: O=C1C(C(N2)=NC3=C2C=NC=C3)=CC4=CC(C)=CC=C4O1
Biological Activity: JMJD6-IN-1 is a JMJD6 inhibitor, with an inhibition rate of 82% at 10 μM. JMJD6-IN-1 inhibits MCF-7 and HCC4006 cell proliferation with IC50 values of 19.2 μM and 25.2 μM. JMJD6-IN-1 inhibits JMJD6 demethylase activity. JMJD6-IN-1 can be used for the research of lung adenocarcinoma, prostate cancer, breast cancer, pancreatic cancer, colon cancer, oral squamous cell carcinoma, and glioblastoma[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JMJD6-IN-1 | 99.17% | JMJD6-IN-1 is a JMJD6 inhibitor, with an inhibition rate of 82% at 10 μM. JMJD6-IN-1 inhibits MCF-7 and HCC4006 cell proliferation with IC50 values of 19.2 μM and 25.2 μM. JMJD6-IN-1 inhibits JMJD6 demethylase activity. JMJD6-IN-1 can be used for the research of lung adenocarcinoma, prostate cancer, breast cancer, pancreatic cancer, colon cancer, oral squamous cell carcinoma, and glioblastoma. | ||||||||||||||||||||
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