923262-96-8
923262-96-8
Chemical Structure
SAR407899 hydrochloride
- CAS No.: 923262-96-8
- Formula:C14H17ClN2O2
- Molecular Weight:280.75
IUPAC Name: 6-(piperidin-4-yloxy)isoquinolin-1(2H)-one hydrochloride
InChIKey: KMNVOGVCCZNVNU-UHFFFAOYSA-N
SMILES: O=C(NC=C1)C(C1=C2)=CC=C2OC3CCNCC3.[H]Cl
Biological Activity: SAR407899 hydrochloride is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively.
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SAR407899 hydrochloride | 99.14% | SAR407899 hydrochloride is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively. | ||||||||||||||||||||
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Keywords
