928046-68-8
Chemical Structure
CTDP-32476
- CAS No.: 928046-68-8
- Formula:C16H25Cl2N
- Molecular Weight:302.28
IUPAC Name: (R)-2-((R)-1-(4-chlorophenyl)-3-methylbutyl)piperidine hydrochloride
InChIKey: OTVLYTHPUXHDAQ-QNBGGDODSA-N
SMILES: [C@@H](CC(C)C)(C1=CC=C(Cl)C=C1)[C@]2(CCCCN2)[H].Cl
Biological Activity: CTDP-32476 is a dopamine transporter (DAT) inhibitor with antidepressant activity, exhibiting a Ki value of 12 nM for human DAT and moderate affinity for the norepinephrine transporter (NET). CTDP-32476 blocks DAT to increase extracellular dopamine levels, and induces locomotor stimulation and brain-stimulation reward effects in rats. CTDP-32476 is used in research related to drug addiction[1].
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CTDP-32476 | CTDP-32476 is a dopamine transporter (DAT) inhibitor with antidepressant activity, exhibiting a Ki value of 12 nM for human DAT and moderate affinity for the norepinephrine transporter (NET). CTDP-32476 blocks DAT to increase extracellular dopamine levels, and induces locomotor stimulation and brain-stimulation reward effects in rats. CTDP-32476 is used in research related to drug addiction. | |||||||||||||||||||||
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