934593-90-5
934593-90-5
Chemical Structure
LW6
Synonym(s): HIF-1α inhibitor; LW8
- CAS No.: 934593-90-5
- Formula:C26H29NO5
- Molecular Weight:435.51
IUPAC Name: methyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate
InChIKey: BJRPPNOJYFZSLY-UHFFFAOYSA-N
SMILES: O=C(OC)C1=CC=C(O)C(NC(COC2=CC=C(C3(C4)CC5CC4CC(C5)C3)C=C2)=O)=C1
Biological Activity: LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor with an IC50 value of 4.4 μM, and it is also an inhibitor of MDH2. LW6 decreases HIF-1α protein expression without affecting HIF-1β expression.
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LW6 | 98.86% | LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor with an IC50 value of 4.4 μM, and it is also an inhibitor of MDH2. LW6 decreases HIF-1α protein expression without affecting HIF-1β expression. | ||||||||||||||||||||
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Keywords
