934593-90-5
934593-90-5
Chemical Structure
LW6
Synonym(s): HIF-1α inhibitor; LW8
- CAS No.: 934593-90-5
- Formula:C26H29NO5
- Molecular Weight:435.51
IUPAC Name: methyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate
InChIKey: BJRPPNOJYFZSLY-UHFFFAOYSA-N
SMILES: O=C(OC)C1=CC=C(O)C(NC(COC2=CC=C(C3(C4)CC5CC4CC(C5)C3)C=C2)=O)=C1
Biological Activity: LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor with an IC50 value of 4.4 μM, and it is also an inhibitor of MDH2. LW6 decreases HIF-1α protein expression without affecting HIF-1β expression.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
LW6 | 98.86% | LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor with an IC50 value of 4.4 μM, and it is also an inhibitor of MDH2. LW6 decreases HIF-1α protein expression without affecting HIF-1β expression. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.66
HY-179434HIF-1α-IN-10 -
Similarity Score 0.63
HY-147791MDH1-IN-2 -
Similarity Score 0.59
HY-111387IDF-11774 -
Similarity Score 0.57
HY-147790MDH1-IN-1 -
Similarity Score 0.56
HY-179691Antiviral agent 75 -
Similarity Score 0.55
HY-123578NSC689857 -
Similarity Score 0.54
HY-W8098875,5-(Adamantane-1,3-diyl)bis(2-methoxybenzoic acid) -
Similarity Score 0.54
HY-100532CD437 -
Similarity Score 0.53
HY-108527RCD1530 (Standard) -
Explore the MedChemAI to find more analogs
