HIF-1α-IN-10
HIF-1α-IN-10 is a ligands for target protein for PROTAC (HIF-1α). HIF-1α-IN-10 can be used to synthesize PROTAC HIF-1α degrader-2 (HY-179424).
For research use only. We do not sell to patients.
- CAS No.: 3095636-66-8
- Formula: C20H23N3O5
- Molecular Weight:385.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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HIF-1α |
HIF-1α PROTAC contains two different ligands connected by a linker; one is an E3 ligase ligand ((S,R,S)-AHPC) (HY-125845), and the other is for Ligands of HIF-1α target protein (HIF-1α-IN-10) (Compound W-1) (HY-179434). PROTAC exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3095636-66-8
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Molecular Weight 385.41
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Formula C20H23N3O5
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SMILES
COC(C1=CC(NC(COC2=CC=C(C=C2)N3CCNCC3)=O)=C(C=C1)O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HIF-1α-IN-10 Related Classifications
HY-179434 Related Classifications
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