950244-33-4
950244-33-4
Chemical Structure
JS6
- CAS No.: 950244-33-4
- Formula:C20H22FN3O3
- Molecular Weight:371.41
InChIKey: QEEPXSHOUBCRGQ-UHFFFAOYSA-N
SMILES: O=C(NCCN1CCOCC1)C2=CC=CC=C2NC(C3=CC=CC=C3F)=O
Biological Activity: JS6 is a Bcl3 inhibitor. JS6 attenuates the binding of Bcl3 to NF-κB1 (p50), disrupts the binding of Bcl3 to NF-κB family proteins p50 and p52, and inhibits the NF-κB signaling pathway. JS6 is applicable to breast cancer-related research[1][2].
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JS6 | 99.49% | JS6 is a Bcl3 inhibitor. JS6 attenuates the binding of Bcl3 to NF-κB1 (p50), disrupts the binding of Bcl3 to NF-κB family proteins p50 and p52, and inhibits the NF-κB signaling pathway. JS6 is applicable to breast cancer-related research. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.59
HY-A0177Fominoben -
Similarity Score 0.54
HY-B0534RMoclobemide (Standard) -
Similarity Score 0.53
HY-183887PD-L1-IN-11 -
Similarity Score 0.53
HY-164675gp120-IN-3 -
Similarity Score 0.53
HY-153017HIF-1 inhibitor-4 -
Similarity Score 0.52
HY-149817AChE-IN-29 -
Similarity Score 0.52
HY-169635Mycobacterium Tuberculosis-IN-6 -
Similarity Score 0.52
HY-112670Exo1 -
Similarity Score 0.52
HY-124491Moquizone -
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