956613-01-7
956613-01-7
Chemical Structure
SB-633825
- CAS No.: 956613-01-7
- Formula:C28H25N3O3S
- Molecular Weight:483.58
IUPAC Name: 4-(5-(6-methoxynaphthalen-2-yl)-1-methyl-2-(2-methyl-4-(methylsulfonyl)phenyl)-1H-imidazol-4-yl)pyridine
InChIKey: ZDSNJSQTPLXCSG-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(C2=NC(C3=CC=NC=C3)=C(C4=CC=C5C=C(OC)C=CC5=C4)N2C)C(C)=C1)(C)=O
Biological Activity: SB-633825 is a potent and ATP-competitive inhibitor of TIE2, LOK (STK10) and BRK with IC50s of 3.5 nM, 66 nM, 150 nM, respectively. SB-633825 can inhibit cancer cell growth and angiogenesis[1].
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SB-633825 | 98.05% | SB-633825 is a potent and ATP-competitive inhibitor of TIE2, LOK (STK10) and BRK with IC50s of 3.5 nM, 66 nM, 150 nM, respectively. SB-633825 can inhibit cancer cell growth and angiogenesis. | ||||||||||||||||||||
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SB-633825 (Standard) | SB-633825 (Standard) is the analytical standard of SB-633825 (HY-108333). This product is intended for research and analytical applications. SB-633825 is a potent and ATP-competitive inhibitor of TIE2, LOK (STK10) and BRK with IC50s of 3.5 nM, 66 nM, 150 nM, respectively. SB-633825 can inhibit cancer cell growth and angiogenesis. | |||||||||||||||||||||
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References
Keywords
