SB-633825 (Standard)

Cat. No.: HY-108333R: Data Sheet Handling Instructions
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SB-633825 (Standard) is the analytical standard of SB-633825 (HY-108333). This product is intended for research and analytical applications. SB-633825 is a potent and ATP-competitive inhibitor of TIE2, LOK (STK10) and BRK with IC₅₀s of 3.5 nM, 66 nM, 150 nM, respectively. SB-633825 can inhibit cancer cell growth and angiogenesis.

For research use only. We do not sell to patients.

SB-633825 (Standard) Chemical Structure

CAS No. : 956613-01-7

Size	Stock	Quantity
1 mg	Get quote 5 - 6 Weeks 4 - 5 Weeks 6 - 7 Weeks 5 - 6 weeks	Estimated Time of Arrival: December 31
5 mg	Get quote 5 - 6 Weeks 4 - 5 Weeks 6 - 7 Weeks 5 - 6 weeks	Estimated Time of Arrival: December 31
10 mg	Get quote 5 - 6 Weeks 4 - 5 Weeks 6 - 7 Weeks 5 - 6 weeks	Estimated Time of Arrival: December 31
25 mg	Get quote 5 - 6 Weeks 4 - 5 Weeks 6 - 7 Weeks 5 - 6 weeks	Estimated Time of Arrival: December 31
50 mg	Get quote 5 - 6 Weeks 4 - 5 Weeks 6 - 7 Weeks 5 - 6 weeks	Estimated Time of Arrival: December 31
100 mg	Get quote 5 - 6 Weeks 4 - 5 Weeks 6 - 7 Weeks 5 - 6 weeks	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Description	SB-633825 (Standard) is the analytical standard of SB-633825 (HY-108333). This product is intended for research and analytical applications. SB-633825 is a potent and ATP-competitive inhibitor of TIE2, LOK (STK10) and BRK with IC₅₀s of 3.5 nM, 66 nM, 150 nM, respectively. SB-633825 can inhibit cancer cell growth and angiogenesis^[1].
IC₅₀ & Target	IC50: 3.5 nM (TIE2), 66 nM (LOK) and 150 nM (BRK)^[1]
Molecular Weight	483.58
Formula	C₂₈H₂₅N₃O₃S
CAS No.	956613-01-7
SMILES	O=S(C1=CC=C(C2=NC(C3=CC=NC=C3)=C(C4=CC=C5C=C(OC)C=CC5=C4)N2C)C(C)=C1)(C)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (269 KB) Handling Instructions (2659 KB)
References	[1]. Elkins JM, et al. Comprehensive characterization of the Published Kinase Inhibitor Set. Nat Biotechnol. 2016 Jan;34(1):95-103. [Content Brief]