957486-82-7

Azido-PEG6-amine Chemical Structure
957486-82-7

Chemical Structure

Azido-PEG6-amine

  • CAS No.: 957486-82-7
  • Formula:C14H30N4O6
  • Molecular Weight:350.41

IUPAC Name: 20-azido-3,6,9,12,15,18-hexaoxaicosan-1-amine

InChIKey: VCQSTKKJKNUQBI-UHFFFAOYSA-N

SMILES: NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Biological Activity: Azido-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG6-amine is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. Azido-PEG6-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No. Product Name Purity Description Pricing
HY-140215 		Azido-PEG6-amine 97.0% Azido-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG6-amine is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG6-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

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