1. PROTAC
  2. PROTAC Linker
  3. NH2-PEG7

NH2-PEG7 

Cat. No.: HY-120918 Purity: ≥98.0%
Handling Instructions

NH2-PEG7 is a PROTAC linker, which refers to the PEG composition. NH2-PEG7 can be used in the synthesis of the PROTAC PARP1 degrader iRucaparib-AP6.

For research use only. We do not sell to patients.

NH2-PEG7 Chemical Structure

NH2-PEG7 Chemical Structure

CAS No. : 1425973-14-3

Size Price Stock Quantity
250 mg USD 180 In-stock
Estimated Time of Arrival: December 31
500 mg USD 300 Get quote
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5 g   Get quote  

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Description

NH2-PEG7 is a PROTAC linker, which refers to the PEG composition. NH2-PEG7 can be used in the synthesis of the PROTAC PARP1 degrader iRucaparib-AP6[1].

IC50 & Target

PEGs

 

Molecular Weight

325.40

Formula

C₁₄H₃₁NO₇

CAS No.

1425973-14-3

SMILES

OCCOCCOCCOCCOCCOCCOCCN

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (307.31 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0731 mL 15.3657 mL 30.7314 mL
5 mM 0.6146 mL 3.0731 mL 6.1463 mL
10 mM 0.3073 mL 1.5366 mL 3.0731 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (7.68 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (7.68 mM); Suspended solution; Need ultrasonic

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.68 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

NH2-PEG7PROTAC LinkerPROTACPEGlinkerInhibitorinhibitorinhibit

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Product Name:
NH2-PEG7
Cat. No.:
HY-120918
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