96392-15-3
96392-15-3
Chemical Structure
PD 117519
Synonym(s): CI947
- CAS No.: 96392-15-3
- Formula:C19H21N5O4
- Molecular Weight:383.40
IUPAC Name: (2R,3R,4S,5R)-2-(6-((2,3-dihydro-1H-inden-2-yl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
InChIKey: NKTIWTYWGRTWOE-NVQRDWNXSA-N
SMILES: OC[C@@H](O1)[C@@H](O)[C@@H](O)[C@@H]1N2C=NC3=C2N=CN=C3NC4CC(C=CC=C5)=C5C4
Biological Activity: PD 117519 (CI947) is an A2A adenosine agonist which has shown oral antihypertensive activity in pharmacological animal models[1][2].
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PD 117519 | 99.94% | PD 117519 (CI947) is an A2A adenosine agonist which has shown oral antihypertensive activity in pharmacological animal models. | ||||||||||||||||||||
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PD 117519 (Standard) | ≥98% | PD 117519 (Standard) is the analytical standard of PD 117519 (HY-100032). This product is intended for research and analytical applications. PD 117519 (CI947) is an A2A adenosine agonist which has shown oral antihypertensive activity in pharmacological animal models. | ||||||||||||||||||||
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References
- [1]. Reynolds DL, et al. Liquid chromatographic analysis of the adenosine agonist PD 117519 in dog plasma. J Pharm Biomed Anal. 1991;9(4):345-9. [Content Brief]
- [2]. Tobin GA, et al. The role of eNOS phosphorylation in causing drug-induced vascular injury. Toxicol Pathol. 2014 Jun;42(4):709-24. [Content Brief]
Keywords
