96969-83-4
96969-83-4
Chemical Structure
JFD00244
- CAS No.: 96969-83-4
- Formula:C30H26N2O4
- Molecular Weight:478.54
IUPAC Name: 1,4-bis((4-hydroxyphenethyl)amino)anthracene-9,10-dione
InChIKey: UUJHFIBEJJLZBF-UHFFFAOYSA-N
SMILES: O=C1C2=C(C=CC=C2)C(C3=C(NCCC4=CC=C(O)C=C4)C=CC(NCCC5=CC=C(O)C=C5)=C13)=O
Biological Activity: JFD00244 is a sirtuin 2 (SIRT2) inhibitor, with anti-tumor effect. JFD00244 is also a Nsp-16 inhibitor against SARS-CoV-2[1][2].
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JFD00244 | 99.40% | JFD00244 is a sirtuin 2 (SIRT2) inhibitor, with anti-tumor effect. JFD00244 is also a Nsp-16 inhibitor against SARS-CoV-2. | ||||||||||||||||||||
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JFD00244 (Standard) | ≥98% | JFD00244 (Standard) is the analytical standard of JFD00244 (HY-108986). This product is intended for research and analytical applications. JFD00244 is a sirtuin 2 (SIRT2) inhibitor, with anti-tumor effect. JFD00244 is also a Nsp-16 inhibitor against SARS-CoV-2. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.64
HY-D0516Solvent Blue 35 -
Similarity Score 0.63
HY-W719653Oil Blue N -
Similarity Score 0.63
HY-13550Ametantrone -
Similarity Score 0.61
HY-116234Solvent Green 3 -
Similarity Score 0.60
HY-13550AAmetantrone acetate -
Similarity Score 0.59
HY-101083BDA-366 -
Similarity Score 0.59
HY-101083A(Rac)-BDA-366 -
Similarity Score 0.59
HY-123020CYD-2-88 -
Similarity Score 0.58
HY-183556NSC156565 -
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References
- [1]. Ciarlo C, A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development. Elife. 2017 Aug 23;6. pii: e29145. [Content Brief]
- [2]. Shankar U, et al. Potential Drugs Targeting Nsp16 Protein May Corroborates a Promising Approach to Combat SARSCoV-2 Virus. ChemRxiv. Cambridge: Cambridge Open Engage; 2020; This content is a preprint and has not been peer-reviewed.
