98570-81-1
Chemical Structure
Cryptanoside A
- CAS No.: 98570-81-1
- Formula:C30H42O10
- Molecular Weight:562.65
IUPAC Name: (1R,3aR,3bR,4aS,5aS,7S,9aS,9bS,10S,11aR)-3a,10-dihydroxy-7-(((2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-9a,11a-dimethyl-1-(5-oxo-2,5-dihydrofuran-3-yl)tetradecahydrocyclopenta[7,8]phenanthro[8a,9-b]oxiren-11(1H)-one
InChIKey: HGZQTHMHTBGLMG-TZUBOXRBSA-N
SMILES: O[C@@]([C@@]1(C2=O)C)(CC[C@]1([H])C(CO3)=CC3=O)[C@]4([C@@](C[C@]5([H])C[C@H]6O[C@H](O[C@H]7C)C[C@@H]([C@H]7O)OC)([H])O4)[C@@]([C@@H]2O)([H])[C@]5(CC6)C
Biological Activity: Cryptanoside A, a cardiac glycoside epoxide, can be isolated from the stems of Cryptolepis dubia. Cryptanoside A has potent cytotoxicity against cancer cells. Cryptanoside A also inhibits Na+/K+-ATPase activity. Cryptanoside A increases the expression of Akt and the p65 subunit of NF-κB[1].
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Cryptanoside A | Cryptanoside A, a cardiac glycoside epoxide, can be isolated from the stems of Cryptolepis dubia. Cryptanoside A has potent cytotoxicity against cancer cells. Cryptanoside A also inhibits Na+/K+-ATPase activity. Cryptanoside A increases the expression of Akt and the p65 subunit of NF-κB. | |||||||||||||||||||||
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Keywords
