1. Membrane Transporter/Ion Channel PI3K/Akt/mTOR NF-κB
  2. Na+/K+ ATPase Akt NF-κB
  3. Cryptanoside A

Cryptanoside A, a cardiac glycoside epoxide, can be isolated from the stems of Cryptolepis dubia. Cryptanoside A has potent cytotoxicity against cancer cells. Cryptanoside A also inhibits Na+/K+-ATPase activity. Cryptanoside A increases the expression of Akt and the p65 subunit of NF-κB.

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Cryptanoside A Chemical Structure

Cryptanoside A Chemical Structure

CAS No. : 98570-81-1

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Description

Cryptanoside A, a cardiac glycoside epoxide, can be isolated from the stems of Cryptolepis dubia. Cryptanoside A has potent cytotoxicity against cancer cells. Cryptanoside A also inhibits Na+/K+-ATPase activity. Cryptanoside A increases the expression of Akt and the p65 subunit of NF-κB[1].

Molecular Weight

562.65

Formula

C30H42O10

CAS No.
SMILES

O[C@@]([C@@]1(C2=O)C)(CC[C@]1([H])C(CO3)=CC3=O)[C@]4([C@@](C[C@]5([H])C[C@H]6O[C@H](O[C@H]7C)C[C@@H]([C@H]7O)OC)([H])O4)[C@@]([C@@H]2O)([H])[C@]5(CC6)C

Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Cryptanoside A
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HY-N9149
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