98891-36-2
98891-36-2
Chemical Structure
L-Homopropargylglycine
- CAS No.: 98891-36-2
- Formula:C6H9NO2
- Molecular Weight:127.14
IUPAC Name: (S)-2-aminohex-5-ynoic acid
InChIKey: SCGJGNWMYSYORS-YFKPBYRVSA-N
SMILES: C#CCC[C@H](N)C(O)=O
Biological Activity: L-Homopropargylglycine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-homopropargylglycine is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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L-Homopropargylglycine | 98.0% | L-Homopropargylglycine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-homopropargylglycine is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor. | ||||||||||||||||||||
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References
- [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 [Content Brief]
- [2]. Shen Y, et al. Protocol for visualizing newly synthesized proteins in primary mouse hepatocytes. STAR Protoc. 2021;2(3):100616. Published 2021 Jun 17. [Content Brief]
Keywords
