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  2. Amino Acid Derivatives
  3. DL-Propargylglycine

DL-Propargylglycine is a Glycine (HY-Y0966) derivative. DL-Propargylglycine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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DL-Propargylglycine Chemical Structure

DL-Propargylglycine Chemical Structure

CAS No. : 50428-03-0

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Based on 1 publication(s) in Google Scholar

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Description

DL-Propargylglycine is a Glycine (HY-Y0966) derivative[1]. DL-Propargylglycine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

In Vitro

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

113.11

Formula

C5H7NO2

CAS No.
Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (884.10 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.8410 mL 44.2048 mL 88.4095 mL
5 mM 1.7682 mL 8.8410 mL 17.6819 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 8.8410 mL 44.2048 mL 88.4095 mL 221.0238 mL
5 mM 1.7682 mL 8.8410 mL 17.6819 mL 44.2048 mL
10 mM 0.8841 mL 4.4205 mL 8.8410 mL 22.1024 mL
15 mM 0.5894 mL 2.9470 mL 5.8940 mL 14.7349 mL
20 mM 0.4420 mL 2.2102 mL 4.4205 mL 11.0512 mL
25 mM 0.3536 mL 1.7682 mL 3.5364 mL 8.8410 mL
30 mM 0.2947 mL 1.4735 mL 2.9470 mL 7.3675 mL
40 mM 0.2210 mL 1.1051 mL 2.2102 mL 5.5256 mL
50 mM 0.1768 mL 0.8841 mL 1.7682 mL 4.4205 mL
60 mM 0.1473 mL 0.7367 mL 1.4735 mL 3.6837 mL
80 mM 0.1105 mL 0.5526 mL 1.1051 mL 2.7628 mL
100 mM 0.0884 mL 0.4420 mL 0.8841 mL 2.2102 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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DL-Propargylglycine Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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DL-Propargylglycine
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