998-07-2
Chemical Structure
1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine
Synonym(s): DMPE
- CAS No.: 998-07-2
- Formula:C33H66NO8P
- Molecular Weight:635.86
IUPAC Name: (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate
InChIKey: NEZDNQCXEZDCBI-WJOKGBTCSA-N
SMILES: CCCCCCCCCCCCCC(O[C@@H](COP(O)(OCCN)=O)COC(CCCCCCCCCCCCC)=O)=O
Biological Activity: 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (DMPE) is a zwitterionic saturated phosphatidylethanolamine bearing two myristoyl (C14:0) chains, and serves as a model membrane component, a neutral lipid component of lipid nanoparticles, and a cocoa butter crystallization nucleating agent. 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine is used in nucleic acid delivery, construction of artificial cell membrane models, and research on urothelial carcinoma[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine | 98.0% | 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (DMPE) is a zwitterionic saturated phosphatidylethanolamine bearing two myristoyl (C14:0) chains, and serves as a model membrane component, a neutral lipid component of lipid nanoparticles, and a cocoa butter crystallization nucleating agent. 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine is used in nucleic acid delivery, construction of artificial cell membrane models, and research on urothelial carcinoma. | ||||||||||||||||||||
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1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (Standard) | ≥98% | 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (DMPE) (Standard) is the analytical standard of 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (DMPE) (HY-W013078). This product is intended for research and analytical applications. 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (DMPE) is a zwitterionic saturated phosphatidylethanolamine bearing two myristoyl (C14:0) chains, and serves as a model membrane component, a neutral lipid component of lipid nanoparticles, and a cocoa butter crystallization nucleating agent. 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine is used in nucleic acid delivery, construction of artificial cell membrane models, and research on urothelial carcinoma. | ||||||||||||||||||||
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1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-d54 | 99.0% | 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (DMPE)-d54 is the deuterated-labeled 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (DMPE) (HY-W013078). 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (DMPE) is a zwitterionic saturated phosphatidylethanolamine bearing two myristoyl (C14:0) chains, and serves as a model membrane component, a neutral lipid component of lipid nanoparticles, and a cocoa butter crystallization nucleating agent. 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine is used in nucleic acid delivery, construction of artificial cell membrane models, and research on urothelial carcinoma. | ||||||||||||||||||||
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References
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[1]. Dorota Matyszewska, et al. The effect of acyl chain length and saturation on the interactions of pirarubicin with phosphatidylethanolamines in 2D model urothelial cancer cell membranes, Journal of Molecular Liquids, Volume 323, 2021, 114633, ISSN 0167-7322.
- [2]. Stobbs JA, et al. Dimyristoylphosphoethanolamine Addition During Chocolate Manufacture Promotes Proper Tempering under Simple Cooling Conditions without Shear. Crystal growth & design. 2025 Jun 18;25(12):4621-4635. [Content Brief]
- [3]. Wang F, et al. Exploring the influence of phospholipid monolayer conformation and environmental conditions on the interfacial binding of Gibberella Zeae lipase. International journal of biological macromolecules. 2019 Jul 01;132:1051-1056. [Content Brief]
- [4]. Xu B, et al. Giant Vesicles Produced with Phosphatidylcholines (PCs) and Phosphatidylethanolamines (PEs) by Water-in-Oil Inverted Emulsions. Life (Basel, Switzerland). 2021 Mar 10;11(3):223. [Content Brief]
